| First Author | Rousseau-Merck MF | Year | 1988 |
| Journal | Hum Genet | Volume | 79 |
| Issue | 2 | Pages | 132-6 |
| PubMed ID | 3292391 | Mgi Jnum | J:19260 |
| Mgi Id | MGI:67447 | Doi | 10.1007/BF00280551 |
| Citation | Rousseau-Merck MF, et al. (1988) The ras-related ral gene maps to chromosome 7p15-22. Hum Genet 79(2):132-6 |
| abstractText | Human cDNAs coding for the new protein ral that shares 50% homology with the ras proteins have been recently isolated. A 600-bp fragment carrying mainly the coding region was used to localize the ral gene by hybridization with sorted chromosomes and in situ hybridization. Direct molecular hybridization on sorted chromosomes using a single laser illumination allowed the assignment of the ral gene to a region of the flow karyotype containing chromosomes 7, 8 and X. With dual laser analysis ral was assigned to the fraction containing chromosome 7. In the 331 human metaphases hybridized with the 3H-labelled insert, the silver grain distribution showed a unique major signal on chromosome 7p15-22. |
