| First Author | Chen PB | Year | 1991 |
| Journal | Infect Immun | Volume | 59 |
| Issue | 12 | Pages | 4706-9 |
| PubMed ID | 1657788 | Mgi Jnum | J:2724 |
| Mgi Id | MGI:51246 | Doi | 10.1128/iai.59.12.4706-4709.1991 |
| Citation | Chen PB, et al. (1991) Experimental Porphyromonas gingivalis infection in nonimmune athymic BALB/c mice. Infect Immun 59(12):4706-9 |
| abstractText | The purpose of this report was to study the role of T lymphocytes following injection of Porphyromonas gingivalis in a mouse abscess model. Three invasive P. gingivalis isolates (ATCC 53977, W83, and AJW4) were injected into athymic BALB/c mice and their heterozygous (nu/+) littermates. The athymic BALB/c (nu/nu) mice were able to localize the invasive P. gingivalis isolates at the injection site. By comparison, the heterozygous BALB/c (nu/+) littermates developed hemorrhagic secondary lesions within 24 h after subcutaneous injection of the same invasive P. gingivalis isolates. These results suggest that naive T lymphocytes may contribute to the pathology associated with P. gingivalis infection. |
