| Primary Identifier | MGI:2686379 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 385354 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in regulation of neuron projection development. Acts upstream of or within negative regulation of stress fiber assembly; positive regulation of lamellipodium assembly; and positive regulation of small GTPase mediated signal transduction. Located in growth cone and neuronal cell body. Is expressed in several structures, including brain; eye; heart; liver; and lung. Used to study congenital nystagmus 1. Human ortholog(s) of this gene implicated in congenital nystagmus 1. Orthologous to human FRMD7 (FERM domain containing 7). PHENOTYPE: Mice homozygous for a null allele lack an optokinetic reflex in the horizontal direction. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
