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Allele : Notch1<tm1Rko> notch 1; targeted mutation 1, Raphael Kopan

Primary Identifier  MGI:1913189 Allele Type  Targeted
Gene  Notch1 Transmission  Germline
Strain of Origin  129X1/SvJ Is Recombinase  false
Is Wild Type  false
molecularNote  Introduction of a point mutation in codon 1744 converting GTG (valine) to GGG (glycine) in exon F. This mutation is predicted to eliminate proteolytic processing of Notch1. There is also a 42 bp pLox site insertion in the intron between exons E and F.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • N1<V-Glox>,
  • N1V1744G,
  • Notch1<tm1Kop>,
  • N1<V-Glox>,
  • N1V1744G,
  • Notch1<tm1Kop>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories

Trail: Allele