Primary Identifier | MGI:3618739 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 723958 |
Mgi Type | miRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including cellular response to forskolin; cellular response to leukemia inhibitory factor; and miRNA-mediated gene silencing by mRNA destabilization. Is expressed in embryo and tail. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human MIR196A2 (microRNA 196a-2). PHENOTYPE: Mice homozygous for a knock-out alele exhibit anterior homeotic transformation with rudimentary rib on the first lumbar vertebrae or anterior homeotic transformation of all sacral elements with posterior displacement of the sacrum. [provided by MGI curators] |