| First Author | Eicher EM | Year | 1978 |
| Journal | Proc Natl Acad Sci U S A | Volume | 75 |
| Issue | 2 | Pages | 946-50 |
| PubMed ID | 273256 | Mgi Jnum | J:5959 |
| Mgi Id | MGI:54436 | Doi | 10.1073/pnas.75.2.946 |
| Citation | Eicher EM, et al. (1978) Assignment of genes to regions of mouse chromosomes. Proc Natl Acad Sci U S A 75(2):946-50 |
| abstractText | A genetic mapping procedure, called the duplication-deficiency method, is described. This method permits the genetic location of a translocation to be determined within a linkage group without the use of recombination. By utilizing the duplication-deficiency method to define the genetic breakpoints for a series of translocations involving a given chromosome and integrating this information with their cytological breakpoints, obtained by Giemsa banding, a genetic map of the chromosomes is constructed whereby groups of loci are assigned to banded regions. Duplication-deficiency mapping and Giemsa banding analysis of the T(X;7)1Ct and T(7;19)145H translocations together with information from the c25H deletion have permitted mouse chromosome 7 to be divided into six and chromosome 19 into two definable genetic regions. |
