Primary Identifier | MGI:6728536 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Pdgfrb |
Transmission | Germline | Strain of Origin | 129S4/SvJaeSor |
Is Recombinase | false | Is Wild Type | false |
molecularNote | LoxP sites were inserted at a BstEII and a HpaI site about 500 base pairs upstream of and 2,100 base pairs downstream from the exons encoding the first and second immunoglobulin domain, respectively. Additionally, a FRT-flanked PGKneo cassette was inserted and then removed by crossing with Gt(ROSA)26Sortm1(FLP1)Dym mice. Cre-mediated recombination removed the floxed segment. |