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Allele : Tg(PTH-CCND1)PC2Anar transgene insertion PC2, Andrew Arnold

Primary Identifier  MGI:3844257 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(PTH-CCND1)PC2Anar
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  5.2 kb of the upstream regulatory region the human PTH gene was used to drive long range tissue specific expression of the full-length 16 kb human cyclin D1 gene in conjunction with its own promoter elements for basal expression. This fusion mimics an inversion found in some human parathyroid adenomas. Three lines were created (1, 2, and 4 with 3, 11, and 15 copies of the transgene, respectively). Line 2 was selected as the representative line.
  • mutations:
  • Insertion
  • synonyms:
  • Tg(PTH-CCND1)2Anar,
  • Tg(PTH-CCND1)2Anar,
  • PC2,
  • PC2
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

7 Publication categories

Trail: Allele