Primary Identifier | MGI:1932127 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 56299 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within regulation of blood vessel branching. Predicted to be located in extracellular region. Is expressed in several structures, including eye; gut; hemolymphoid system; male reproductive gland or organ; and nervous system. Orthologous to human FKBPL (FKBP prolyl isomerase like). PHENOTYPE: Homozygous inactivation of this gene leads to complete embryonic lethality. Heterozygotes develop normally but exhibit enhanced angiogenesis in various experimental and tumor disease models. [provided by MGI curators] |