Primary Identifier | MGI:2677436 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 386611 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ubiquitin protein ligase activity. Involved in protein autoubiquitination. Located in endoplasmic reticulum membrane. Is expressed in several structures, including brain; male reproductive gland or organ; respiratory system; submandibular gland; and thymus. Orthologous to human RNF133 (ring finger protein 133). PHENOTYPE: Homozygous null males show severely reduced fertility, with abnormal sperm morphology and motility. [provided by MGI curators] |