| Type | MGI:General | Description | at 4 weeks postinfection with 2 x 103 organisms of B. burgdorferi (N40 isolate), homozygotes exhibit a striking increase in rear ankle swelling relative to wild-type and heterozygous controls, with both rear ankle joints showing uniformly increased edema; however, individual disease parameters and overall arthritic lesion severity is not significantly different between similarly-infected mutant and control mice |