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Protein Coding Gene : Ptprf protein tyrosine phosphatase receptor type F

Primary Identifier  MGI:102695 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  19268
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables chondroitin sulfate proteoglycan binding activity. Acts upstream of or within neuron projection regeneration and regulation of axon regeneration. Located in neuron projection and neuronal cell body. Is expressed in several structures, including adrenal gland; alimentary system epithelium; central nervous system; genitourinary system; and nasal cavity epithelium. Human ortholog(s) of this gene implicated in hyperinsulinism. Orthologous to human PTPRF (protein tyrosine phosphatase receptor type F).
PHENOTYPE: Homozygous null females have premature involution of the mammary glands leading to an inability to feed pups. Other characteristics of null mice include defective nerve regeneration and hyperactivity. [provided by MGI curators]
  • synonyms:
  • LAR,
  • MGD-MRK-19599,
  • MGI:2140169,
  • AA591035,
  • RPTP-LAR,
  • protein tyrosine phosphatase receptor type F,
  • expressed sequence AA591035,
  • Ptprf

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For