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Protein Coding Gene : Tns1 tensin 1
Primary Identifier  MGI:104552 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  21961
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.4.0)

Predicted to enable actin binding activity. Acts upstream of or within cell-substrate junction assembly and fibroblast migration. Located in focal adhesion. Is expressed in several structures, including future brain; gut; heart; metanephros; and yolk sac. Orthologous to human TNS1 (tensin 1).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced female fertility, and develop kidney cysts and progressive kidney degeneration that may lead to death from renal failure. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA E030037J05 gene,
  • MGI:1915754,
  • RIKEN cDNA 1110018I21 gene,
  • expressed sequence AI648117,
  • 1110018I21Rik,
  • MGI:2138313,
  • RIKEN cDNA E030018G17 gene,
  • Tns,
  • 1200014E20Rik,
  • E030037J05Rik,
  • tensin 1,
  • AI648117,
  • Tns1,
  • RIKEN cDNA 1200014E20 gene,
  • E030018G17Rik,
  • MGD-MRK-25984,
  • MGI:1918975,
  • MGI:2444104
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Trail: ProteinCodingGene

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1 Driver For

Trail: ProteinCodingGene




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