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Protein Domain : Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily

Primary Identifier  IPR042556 Type  Homologous_superfamily
Short Name  AZUL_sf
description  The AZUL or amino-terminal zinc-binding domain of ubiquitin E3a ligase (Ube3A) is found in eukaryotes, and is an unusual zinc-finger domain. The final cysteine is usually mutated in Angelman syndrome patients. It is likely that AZUL plays a role in Ube3A substrate-recognition [].The AZUL domain has a helix-loop-helix architecture with a Zn ion coordinated by four Cys residues arranged in Cys-X(4)-Cys-X(4)-Cys-X(28)-Cys motif [].

0 Child Features

0 Parent Features

6 Protein Domain Regions