| Primary Identifier | IPR033316 | Type | Family |
| Short Name | RBBP8-like |
| description | This entry includes DNA endonuclease RBBP8 from animals, Ctp1 from fission yeast and protein gamma response 1 from plants []. This entry also includes human RBBP8 N-terminal-like protein (RBBP8NL) whose function is not clear. RBBP8 is an endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in processing meiotic and mitotic double-strand breaks (DSBs) by ensuring both resection and intrachromosomal association of the broken ends []. Ctp1 is an endonuclease that cooperates with the MRN complex in processing meiotic and mitotic double-strand breaks by allowing the endonucleolytic removal of rec12 from the break sites and ensuring both resection and intrachromosomal association of the broken ends []. |
