Primary Identifier | MGI:6513050 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Abcg4 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting vector is designed to insert a loxP-flanked neomycin cassette and an EGFP reporter onto a portion of exon 7 (prior to the transmembrane domains) and to replace all of exon 8. Northern analysis of liver, lung, spleen, heart, eye, brain, testes, and kidney detected multiple short transcripts. Cre-mediated recombination removed the floxed neo cassette. The EGFP reporter does not appear to express. |