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Publication : PLP-I: a novel prolactin-like gene in rodents.

First Author  Hiraoka Y Year  1999
Journal  Biochim Biophys Acta Volume  1447
Issue  2-3 Pages  291-7
PubMed ID  10542329 Mgi Jnum  J:58253
Mgi Id  MGI:1347138 Doi  10.1016/s0167-4781(99)00160-8
Citation  Hiraoka Y, et al. (1999) PLP-I: a novel prolactin-like gene in rodents. Biochim Biophys Acta 1447(2-3):291-7
abstractText  In this report, we describe molecular cloning and characterization of cDNAs encoding a novel rat prolactin-like protein. The rat cDNAs were isolated from the decidua and the gene was named PLP-I. cDNAs for the mouse equivalent were also cloned by the cross-hybridization technique. Pregnancy-specific expression of the rat PLP-I gene was observed in the rat placenta by Northern analysis. Location of signal peptide cleavage sites in rat and mouse pre-PLP-I proteins was predicted using a theoretical method. A molecular phylogenetic tree for the growth hormone-prolactin superfamily including the novel member, PLP-I, constructed using the neighbor-joining method, places rat/mouse PLP-I closest to rat/mouse placental lactogen I and II.
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