Primary Identifier | MGI:2146901 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 106628 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to enable identical protein binding activity. Predicted to be involved in epithelial to mesenchymal transition; negative regulation of cardiac muscle cell apoptotic process; and positive regulation of cell growth involved in cardiac muscle cell development. Predicted to act upstream of or within endocytosis. Predicted to be located in nucleoplasm. Is expressed in several structures, including clavicle; cranium; inner ear; submandibular gland primordium; and trigeminal ganglion. Orthologous to human TRIP10 (thyroid hormone receptor interactor 10). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased insulin-stimulated glucose uptake in adipocytes and decreased circulating glucose levels. Mice homozygous for another knock-out allele exhibit impaired integrin-dependent T-cell trafficking. [provided by MGI curators] |