Primary Identifier | MGI:3619422 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 723875 |
Mgi Type | miRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in energy homeostasis. Acts upstream of or within cellular response to leukemia inhibitory factor. Is expressed in several structures, including bone; central nervous system; dorsal root ganglion; liver; and neural retina. Orthologous to human MIR485 (microRNA 485). PHENOTYPE: Mice homozygous for a null allele exhibit fewer, larger brown fat cell, insulin resistance, and impaired glucose tolerance whether fed standard chow or a high-fat diet under cold conditions. [provided by MGI curators] |