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Publication : The allograft inflammatory factor-1 family of proteins.

First Author  Deininger MH Year  2002
Journal  FEBS Lett Volume  514
Issue  2-3 Pages  115-21
PubMed ID  11943136 Mgi Jnum  J:76014
Mgi Id  MGI:2178211 Doi  10.1016/s0014-5793(02)02430-4
Citation  Deininger MH, et al. (2002) The allograft inflammatory factor-1 family of proteins. FEBS Lett 514(2-3):115-21
abstractText  The allograft inflammatory factor-1 (AIF-1) is a 17 kDa interferon-gamma-inducible Ca(2+)-binding EF-hand protein that is encoded within the HLA class III genomic region. Three proteins are probably identical with AIF-1 termed Iba1 (ionized Ca(2+)-binding adapter), MRF-1 (microglia response factor) and daintain. Considerable but not complete sequence identity with AIF-1 has been described for IRT-1 (interferon-responsive transcript), BART-1 (balloon angioplasty-responsive transcript), and other, yet unassigned alternatively spliced variants. In this review, genomic and functional characteristics of AIF-1-related proteins are summarized and a common nomenclature is proposed.
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