Primary Identifier | MGI:6415027 | Allele Type | Endonuclease-mediated |
Attribute String | Humanized sequence | Gene | Scn11a |
Strain of Origin | C57BL/6NCrSlc | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology generated a phenylalanine to cysteine substitution at amino acid 802 (F802C). This corresponds to the human F814C mutation identified in familial episodic pain. |