| First Author | Blum K | Year | 1987 |
| Journal | Experientia | Volume | 43 |
| Issue | 4 | Pages | 408-10 |
| PubMed ID | 3569490 | Mgi Jnum | J:32306 |
| Mgi Id | MGI:79805 | Doi | 10.1007/BF01940430 |
| Citation | Blum K, et al. (1987) Regional brain [Met]-enkephalin in alcohol-preferring and non-alcohol-preferring inbred strains of mice. Experientia 43(4):408-10 |
| abstractText | Scrutiny of the data from these studies reveals that the C58/J alcohol-preferring mice have significantly lower baseline methionine-enkephalin levels in both the corpus striatum and hypothalamus compared to C3H/CHRGL/2 non-alcohol-preferring mice. In other brain regions in these two strains, specifically, pituitary, amygdala, midbrain, and hippocampus, analysis of methionine-enkephalin levels did not show any significant differences. This suggests that the hypothalamus may indeed be a specific locus involved in the regulation of alcohol intake, via the molecular interaction between neuroamines, opioid peptides, as they are influenced by genetics and environment. |
