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Allele : Aire<tm2Mmat> autoimmune regulator; targeted mutation 2, Mitsuru Matsumoto
Primary Identifier  MGI:3818933 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Aire
Transmission  Germline Strain of Origin  (C57BL/6NCrlj x CBA/JNCrlj)F1
Is Recombinase  false Is Wild Type  false
molecularNote  Genomic sequence from immediately after the Kozak sequence in exon 1 to the exon 2 was replaced with GFP and a floxed neo cassette via homologous recombination. The neo cassette was removed via in vivo Cre mediated recombination. Immunohistochemical analysis in heterozygous mice indicates that the pattern of GFP expression is similar to the pattern of endogenous gene expression.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Aire<gfp>,
  • Aire<gfp>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

11 Publication categories

Trail: Allele




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