Primary Identifier | MGI:5828555 | Allele Type | Targeted |
Attribute String | Conditional ready | Gene | F2rl1 |
Transmission | Germline | Strain of Origin | C57BL/6NTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Arginine codon 38 (AGA) in exon 2 was changed to glutamic acid (GAG) (p.R38E). Exon 2 was flanked by loxP sites. The FRT site flanked selection cassette that was inserted was removed through subsequent Flp-mediated recombination. The mutation renders the encoded peptide cleavage-resistant. |