Primary Identifier | MGI:2384630 | Allele Type | Targeted |
Attribute String | Reporter | Gene | Cd79a |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 2 through 5 were replaced by a fragment flanked by inverted loxP sites containing the cDNA for exons 2 through 5 followed downstream by a polyA signal and, in opposite orientation, sequence encoding a membrane-associated enhanced green fluorescent protein (GFP). The absence of GFP and the expression of endogenous protein was confirmed by flow cytometric analysis of bone marrow, spleen, and lymph node cells. |