|  Help  |  About  |  Contact Us

Allele : Atr<tm1.1Twgl> ataxia telangiectasia and Rad3 related; targeted mutation 1.1, Thomas W Glover

Primary Identifier  MGI:3851821 Allele Type  Targeted
Attribute String  Humanized sequence, Hypomorph Gene  Atr
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A transition mutation in exon 9 replaces a G with an A. This mutation replicates one identified in human patients with Seckel syndrome 1 that disrupts splicing. An frt flanked neo cassette was inserted upstream of exon 8 that was removed by germ line, flp mediated recombination. Western blot analysis confirmed normal protein expression.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • Atr<Sck1>,
  • Atr<Sck1>
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele