| Primary Identifier | MGI:6189110 | Allele Type | Targeted |
| Attribute String | Inserted expressed sequence | Gene | Dp(19Rln1-Gldc)2Uru |
| Transmission | Germline | Strain of Origin | (C57BL/6 x 129S4/SvJae)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The donor constructed mice with a 0.9-Mb deletion on mouse chromosome 19 syntenic with the human 9p24.1 region by trans-allelic recombination in vivo. The deletion includes the genes Rln1, Plgrkt, Cd274, Pdcd1lg2, Ric1, Ermp1, Mlana, 9930021J03Rik, Ranbp6, Il33, Trpd52l3, Uhrf2, and Gldc. Briefly, the donor inserted loxP sites into the mouse genome by targeting sites to flank the region to duplicate or delete. Cre-mediated recombination duplicated the intervening sequence. |
