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Allele : Ucp3<tm1Lowl> uncoupling protein 3 (mitochondrial, proton carrier); targeted mutation 1, Bradford B Lowell

Primary Identifier  MGI:2183166 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ucp3
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A 700 bp genomic fragment containing part of exons 2 and 3 was replaced with a neomycin selection cassette. RNase protection analysis on RNA derived from skeletal muscle and brown adipose tissue of homozygous mice confirmed that no detectable transcript was expressed from this allele. Western blot analysis confirmed the absence of detectable protein in skeletal muscle mitochondria of homozygous mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

11 Publication categories

Trail: Allele