| First Author | Dumortier O | Year | 2013 |
| Journal | Cell Metab | Volume | 18 |
| Issue | 3 | Pages | 312-24 |
| PubMed ID | 23850315 | Mgi Jnum | J:202708 |
| Mgi Id | MGI:5521254 | Doi | 10.1016/j.cmet.2013.06.004 |
| Citation | Dumortier O, et al. (2013) MicroRNAs and metabolism crosstalk in energy homeostasis. Cell Metab 18(3):312-24 |
| abstractText | In record time, microRNAs (miRNAs) have acquired the respected stature of important natural regulators of global gene expression. Multiple studies have demonstrated that a large number of miRNAs are under the control of various metabolic stimuli, including nutrients, hormones, and cytokines. Conversely, it is now well recognized that miRNAs control metabolism, thereby generating a bidirectional functional link, which perturbs energy homeostasis in case of disconnection in the miRNA-metabolism interplay. A challenging road lies ahead for defining the role of miRNAs in the pathogenesis of diseases such as diabetes and for establishing their usefulness as new medications and clinically reliable biomarkers. |
