Primary Identifier | MGI:101836 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 22029 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to enable enzyme binding activity; identical protein binding activity; and tumor necrosis factor receptor binding activity. Predicted to be involved in protein K63-linked ubiquitination; regulation of signal transduction; and tumor necrosis factor-mediated signaling pathway. Predicted to act upstream of or within apoptotic process. Predicted to be active in cytoplasm and cytoplasmic side of plasma membrane. Is expressed in jaw and urinary system. Orthologous to human TRAF1 (TNF receptor associated factor 1). PHENOTYPE: Homozygous null mice exhibit abnormal T cell functionality. [provided by MGI curators] |