| First Author | von Deimlimg O | Year | 1991 |
| Journal | Mouse Genome | Volume | 89 |
| Pages | 549 | Mgi Jnum | J:14310 |
| Mgi Id | MGI:62481 | Citation | von Deimlimg O, et al. (1991) Esterase-29. Mouse Genome 89:549 |
| abstractText | Research News. Esterase-29. Following disc electrophoresis of serum, genetic variation in activity of a single-banded carboxylesterase termed esterase-29 (ES-29) was detected. Three phenotypes were distinguished. ES-29A is a null type and was found in SEG/l, a partly inbred (F14) line of M.spretus. ES-29B designates strong expression and is widely distributed among laboratory inbred strains such as BALB/cJ. ES-29C comigrates with ES-29B but is only weakly expressed. It was found in MOLF/Ei and in other derivatives of M.m.molossinus. Es-29 is considered to be a structural locus. Esterase modifying locus-1 (Mse-1). ES-29 (see above) appeared as a double band in the experimental strain LFA/Fre (this strain was described by Scherer et al., Genomics 5, 275, 1989). The more anodal band of this doublett could not be distinguished from the above described ES-29B. A presumably modifying locus termed Mse-1, was found to control presence (Mse-1m) or absence (Mse-1a) of the second band. Backcrosses involving LFA/Fre and BALB/cJ revealed that Mse-1 is very closely linked to Pre-2 on chromosome 12. The allele m originates from wild M.m.molossinus which we obtained from V.Chapman in 1977. The same allele was also observed in MOL3/JA and in Cas-Bgr; the latter strain was kindly supplied by K. Moriwaki. |
