| Primary Identifier | MGI:2384494 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Pitx2 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The gene was disrupted by replacement of the entire homeodomain and C-terminus with an in-frame lacZ-neo cassette via homologous recombination. Southern blot analysis identified homozygous mutant embryos up to E15. X-gal staining of mutant embryos demonstrated the expression pattern of the lacZ targeted insert is similar to that of endogenous protein. |
