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Allele : Htr2c<tm1Arte> 5-hydroxytryptamine (serotonin) receptor 2C; targeted mutation 1, TaconicArtemis

Primary Identifier  MGI:5751109 Allele Type  Targeted
Gene  Htr2c Transmission  Germline
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  The 52 bp exon complementary sequence (ECS) in intron 5 was deleted. The GU1 splice donor site cgGtatgta was also mutated to cgCtatgta. These mutations inhibit the formation of a double-stranded RNA structure and the action of the ADAR enzyme (Adenosine Deaminase Acting on RNA).
  • mutations:
  • Nucleotide substitutions,
  • Intragenic deletion
  • synonyms:
  • Htr2c INI,
  • Htr2c INI
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele