Primary Identifier | MGI:5751109 | Allele Type | Targeted |
Gene | Htr2c | Transmission | Germline |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The 52 bp exon complementary sequence (ECS) in intron 5 was deleted. The GU1 splice donor site cgGtatgta was also mutated to cgCtatgta. These mutations inhibit the formation of a double-stranded RNA structure and the action of the ADAR enzyme (Adenosine Deaminase Acting on RNA). |