| Primary Identifier | MGI:1855691 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 53608 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable ATP binding activity; MAP kinase kinase kinase activity; and magnesium ion binding activity. Predicted to be involved in MAPK cascade. Predicted to act upstream of or within phosphorylation. Is expressed in heart and vibrissa. Orthologous to human MAP3K6 (mitogen-activated protein kinase kinase kinase 6). PHENOTYPE: Homozygous and heterozygous null mice display an increased incidence of chemically induced skin tumors and homozygous mice also show resistance to induced apoptosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
