| Primary Identifier | IPR035557 | Type | Domain |
| Short Name | SNX18_SH3 |
| description | Sorting nexin-18 (SNX18) is localized to peripheral endosomal structures, and acts in a trafficking pathway that is clathrin-independent but relies on AP-1 and PACS1 []. It binds FIP5 and is required for apical lumen formation []. It may also play a role in axonal elongation []. SNXs are Phox homology (PX) domain containing proteins that are involved in regulating membrane traffic and protein sorting in the endosomal system [, ]. SNX18 also contains BAR and SH3 domains.This entry represent the SH3 domain of SNX18. |
