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Protein Domain : Regulatory protein NPR

Primary Identifier  IPR044292 Type  Family
Short Name  NPR
description  This entry represents a group of plant regulatory proteins, including NPR1-4 from Arabidopsis. NPR1 is a central regulator of salicylic-acid (SA)-mediated defense signaling in Arabidopsis. It contains a BTB/POZ domain at the N-terminal and an ankyrin-repeat domain in the central region. It binds to TGA1, a member of the TGA family of transcription factors that activate SA-responsive elements in the promoters of PR (PATHOGENESIS-RELATED) genes. It also has cytosolic function in cross-communication between SA- and JA-dependent defense signaling pathways []. NPR1 is functionally conserved in diverse plant species, including rice (Oryza sativa L.) []. NPR3 and NPR4 have also been shown to be required for basal defense against pathogens [, ].

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