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Publication : DNA sequence analysis of the cytosolic acetaldehyde dehydrogenase gene (Ahd-2) in mouse strains with variable ethanol preferences.

First Author  Bond SL Year  1994
Journal  Biochem Med Metab Biol Volume  52
Issue  2 Pages  155-9
PubMed ID  7993664 Mgi Jnum  J:20371
Mgi Id  MGI:68465 Doi  10.1006/bmmb.1994.1048
Citation  Bond SL, et al. (1994) DNA sequence analysis of the cytosolic acetaldehyde dehydrogenase gene (Ahd-2) in mouse strains with variable ethanol preferences. Biochem Med Metab Biol 52(2):155-9
abstractText  Differences in Ahd-2 at the DNA sequence level were characterized in mouse strains with variable ethanol preferences. The 5' region and the region surrounding the active site of Ahd-2 were compared to detect differences which could affect ethanol sensitivity. Only minor differences were found among the strains in the two regions. These differences cannot explain their variable ethanol preference and the implications of sequence identities among the divergent strains in these regions has yet to be determined.
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