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Protein Coding Gene : Adgrg6 adhesion G protein-coupled receptor G6

Primary Identifier  MGI:1916151 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  215798
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables laminin binding activity. Involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; heart trabecula formation; and myelination in peripheral nervous system. Predicted to be located in cell surface; cytoplasm; and plasma membrane. Is expressed in several structures, including embryo mesenchyme; heart; musculoskeletal system; urinary system; and vascular system. Used to study idiopathic scoliosis. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome. Orthologous to human ADGRG6 (adhesion G protein-coupled receptor G6).
PHENOTYPE: Mice homozygous for a null mutation die during organogenesis and display signs of circulatory failure. [provided by MGI curators]
  • synonyms:
  • AI449247,
  • MGI:2143604,
  • 1190004A11Rik,
  • LOC215798,
  • Adgrg6,
  • Gpr126,
  • AW045736,
  • G protein-coupled receptor 126,
  • expressed sequence AW045736,
  • RIKEN cDNA 1190004A11 gene,
  • gene model 222, (NCBI),
  • MGI:2143793,
  • expressed sequence AI449247,
  • DREG,
  • adhesion G protein-coupled receptor G6,
  • MGI:2685068,
  • Gm222

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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