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Comment :

Type  MGI:General Description  with lower doses of LPS (18.75 and 9.38 mg/kg) mortality is delayed or reduced, respectively, compared to wild-type mice however with a high dose of LPS ((37.5 mg/kg) no difference in the time course of incidence of mortality is seen and the time course of macrophage cell death in response to Salmonella tymphimurium is similar to wild-type