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Publication : Susceptibility of different strains of mice to South American rattlesnake (Crotalus durissus terrificus) venom: correlation between lethal effect and creatine kinase release.

First Author  Lima MR Year  1991
Journal  Toxicon Volume  29
Issue  6 Pages  783-6
PubMed ID  1926179 Mgi Jnum  J:27011
Mgi Id  MGI:74429 Doi  10.1016/0041-0101(91)90070-8
Citation  Lima MR, et al. (1991) Susceptibility of different strains of mice to South American rattlesnake (Crotalus durissus terrificus) venom: correlation between lethal effect and creatine kinase release. Toxicon 29(6):783-6
abstractText  In the present work we report that susceptibility to Crotalus durissus terrificus venom: varies according to the strain of inbred mouse used. The s.c. LD50 for Balb/c and C57BI/6 mice were 193 micrograms/kg and 171 micrograms/kg, whereas for A/J and DBA/J they were 78 micrograms/kg and 74 micrograms/kg, respectively. In addition, a direct correlation between susceptibility to C. d. terrificus venom and creatine kinase serum levels (CK) was observed.
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