Primary Identifier | MGI:5696384 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Cd74-Nlrc4*)1Kyas |
Strain of Origin | C57BL/6N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The mouse Nlrc4 cDNA with a mutation equivalent to the human A to C transversion at position 1589 in exon 4 (changing a histidine to a proline at position 443) and three HA tags is under the control of an invariant chain promoter. Three lines were created: 1, 2, and 3. Line one shows an approximate 3.1-fold increase in Nlrc4 levels in the spleen compared to endogenous levels. |