| Primary Identifier | MGI:3530442 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Aph1c |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Cre mediated recombination excised exons 3 and 4 from Aph1ctm1Bdes, resulting in deletion of exons 3 and 4 and a frame shift in the ORF, subsequently deleting amino acids from 96 on. RT-PCR and Western blot of mutant MEFs demonstrated the lack of expression of mRNA or protein, respectively. |
