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Publication : Cloning of a cDNA coding for porcine zona pellucida glycoprotein ZP1 and its genomic organization.

First Author  Taya T Year  1995
Journal  Biochem Biophys Res Commun Volume  207
Issue  2 Pages  790-9
PubMed ID  7864874 Mgi Jnum  J:22967
Mgi Id  MGI:70835 Doi  10.1006/bbrc.1995.1256
Citation  Taya T, et al. (1995) Cloning of a cDNA coding for porcine zona pellucida glycoprotein ZP1 and its genomic organization [published erratum appears in Biochem Biophys Res Commun 1995 Sep 14;214(2):754]. Biochem Biophys Res Commun 207(2):790-9
abstractText  The zona pellucida composed of three or four glycoproteins plays important roles in fertilization. Our previous study showed that porcine ZP1, one of the major glycoproteins of porcine zona pellucida, was divided into two components (porcine ZP4 and ZP2), and suggested it was a homologue of mouse ZP2. In this paper we report the cloning of a cDNA for porcine ZP1 and its genomic organization. The deduced amino acid sequence of porcine ZP1 shared a 54% and 63% identity with those of mouse and human ZP2, respectively. Genomic organization of porcine ZP1 was also similar to that of mouse ZP2. The transcript of porcine ZP1 gene was detected only in growing oocytes.
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