Primary Identifier | MGI:3045350 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 244723 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in neurotransmitter receptor localization to postsynaptic specialization membrane. Acts upstream of or within locomotory behavior and visual perception. Located in synaptic membrane. Part of AMPA glutamate receptor complex. Is active in glutamatergic synapse. Is extrinsic component of postsynaptic density membrane. Is expressed in several structures, including central nervous system; eye; and orbito-sphenoid. Orthologous to human OLFM2 (olfactomedin 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit moderate locomotor and anxiety-related behavioral abnormalities, altered visual evoked potential, and reduced compactness of myelin sheaths in the optic nerve. [provided by MGI curators] |