Primary Identifier | MGI:5788290 | Allele Type | Targeted |
Attribute String | Inserted expressed sequence, Null/knockout | Gene | Tex19.1 |
Transmission | Germline | Strain of Origin | (C57BL/6 x 129S4/SvJae)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The open coding region in exon 3 was replaced with the Tex11 open reading frame with a T to A point mutation that results in the amino acid substitution of arginine for tryptophan at position 118. This mutation corresponds to a mutation in sterile human males. Cre-mediated recombination removed the selection cassette inserted downstream of the inserted expressed sequence. |