Primary Identifier | MGI:1919135 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 71885 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to enable DNA binding activity. Predicted to be involved in interstrand cross-link repair. Predicted to act upstream of or within DNA repair. Predicted to be located in cytosol. Predicted to be part of chromatin. Predicted to be active in nucleoplasm. Is expressed in bladder; bone; nervous system; rib; and tail paraxial mesenchyme. Orthologous to human FAAP100 (FA core complex associated protein 100). PHENOTYPE: Mice homozygous for a null allele exhibit primordial germ cell loss at E9.5 associated with increased DNA damage and apoptosis. [provided by MGI curators] |