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Allele : Selp<tm1Bay> selectin, platelet; targeted mutation 1, Baylor College of Medicine
Primary Identifier  MGI:1857244 Allele Type  Targeted
Attribute String  Null/knockout Gene  Selp
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance gene was inserted in the reverse orientation to delete a 4.5kb region containing exons 3 through 5. RT-PCR analysis of lung RNA isolated from homozygous mutant mice showed a transcript 682 base pairs shorter than normal. Immunohistochemical staining showed a lack of encoded protein on both endothelium and platelets.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • P-,
  • P-sel<->,
  • CD62P<->,
  • P-sel<->,
  • CD62ELP<->,
  • CD62ELP<->,
  • P-,
  • CD62P<->,
  • P-selectin<->,
  • P-selectin<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

9 Carried By

Trail: Allele

0 Driven By

140 Publication categories

Trail: Allele




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