| Primary Identifier | IPR038028 | Type | Family |
| Short Name | BPTF |
| description | This entry includes the nucleosome-remodeling factor subunits BPTF (vertebrates) and NURF301 (Drosophila melanogaster), which are components of the NURF (nucleosome-remodeling factor) complex [, ]. The NURF complex catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin []. The HMGA/HMGI(Y)-like DNA-binding site of NURF301 facilitates nucleosome sliding []. BPTF binds histone H3K4me3 via its PHD zinc finger domain [], and interacts with the myc-associated zinc finger protein MAZ, altering its transcriptional activity, []and the Kelch-like Ech-associated protein KEAP1 []. |
