Primary Identifier | IPR046795 | Type | Domain |
Short Name | TMEM127_TM |
description | Transmembrane protein 127 (TMEM127) modulates mTOR function in the endolysosome. Its interaction with early endosomal GTPase Rab5 to inhibit mTOR signalling seems to be related with its tumour-suppressing properties [, ]. This entry represents the transmembrane region of this protein and similar animal sequences. |