Primary Identifier | MGI:1330842 | Organism | Mus musculus |
Chromosome | 5 | NCBI Gene Number | 19415 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 5.4.0) Predicted to enable GTPase activator activity; metal ion binding activity; and phospholipid binding activity. Predicted to be involved in positive regulation of dendrite extension. Predicted to act upstream of or within cell differentiation. Predicted to be located in cytosol. Predicted to colocalize with plasma membrane. Is expressed in telencephalon mantle layer. Orthologous to human RASAL1 (RAS protein activator like 1). PHENOTYPE: Mice homozygous for a hypomorphic allele exhibit increased kidney fibrosis upon challenge with unilateral ureteral obstruction. [provided by MGI curators] |